Supply Fructus Cnidii Extract Powder 10%/50%/90%/98% Osthole
Product Description
Supply Fructus Cnidii Extract Powder 10%/50%/90%/98% Osthole
Product Name | Cnidium monnieri Extract Osthole |
Exterior | White, light yellow, brownish yellow powder |
Active Ingredient | Osthole 10%, 50%, 90%, 98% |
Test Method | HPLC |
Extraction Solvent | Ethanol |
CAS NO | 482-12-8 |
Molecular Formula | C15H16O3 |
Molecular Weight | 244.29 |
Osthol, also known as methoxyparsley, parsley methyl ether, is a coumarin compounds, in the umbrella plant
osthol content is high,so called osthol. In 1909, Herzog and Krohn first obtained the compound osthol from the
roots of the umbrella plant europhus. At present, it is widely found in plants, mainly in umbelliferae and rutaceae,
and also in a few compositae and legumes. Commercial cnidium cnidium is mainly extracted from dried and ripe
fruit of cnidium cnidium. Cnidium is mainly distributed in guangxi, jiangsu, anhui, shandong, hebei, etc. Because
of its various biological activities, cnidium is widely used in cosmetics, medicine and agriculture.
Specifiaction:
Osthol : 10%, 50%, 90% 98% by HPLC
osthol content is high,so called osthol. In 1909, Herzog and Krohn first obtained the compound osthol from the
roots of the umbrella plant europhus. At present, it is widely found in plants, mainly in umbelliferae and rutaceae,
and also in a few compositae and legumes. Commercial cnidium cnidium is mainly extracted from dried and ripe
fruit of cnidium cnidium. Cnidium is mainly distributed in guangxi, jiangsu, anhui, shandong, hebei, etc. Because
of its various biological activities, cnidium is widely used in cosmetics, medicine and agriculture.
Specifiaction:
Osthol : 10%, 50%, 90% 98% by HPLC
Antiarrhythmic effect
Water extract and total coumadin from fructus cnidium have obvious preventive effects on chloroform
induced ventricular fibrillation in mice and calcium chloride induced ventricular fibrillation in rats. Fructus
cnidium and zanthoxylum acetaminophen also have this pharmacological effect and can improve ventricular
electrofibrillation threshold in rabbits. The water extract, total coumarin, cnidium, and phenols of zanthoxylum
had significant inhibitory effects on the flow of sodium ions in the myocardial cell membrane.
Antihypertensive, inhibition of vascular dilatation
Osthol had a dose-dependent negative inotropic effect on the left atrium of isolated guinea pigs and a negative
frequency effect on the left atrium of isolated guinea pigs. In addition to the polarization induced by norepinephrine,
CaCl2 and high K+, the aorta contraction dose-response curve of rabbits was shifted to the right and the maximum
response was decreased, indicating the role of biosynthetic compound in relaxing vascular smooth muscle. Fructus
cnidium has a certain antihypertensive effect.
Effects on respiratory system
Cnidium monnieri total coumarin with relaxation by drugs (histamine and acetylcholine) caused by bronchial
spasms and diastole bronchus role directly, this function can be B - adrenaline receptor blockers block by propranolol,
mice after total coumarin cnidium monnieri, obviously increase the amount of phenol red drain in the body, shows
strong expectoranting action.
Anti-Inflammatory effects
Cnidium cnidium and phenolic zanthoxylum could inhibit the ear shell swelling of mice caused by xylene and the
increase of capillary permeability in abdominal cavity caused by acetic acid. Osthol and acetonol had significant
inhibitory effects on foot swelling in rats and rats with bilateral adrenal resection. Osthol could also reduce the PGE
content in the inflammatory tissues of the swollen part of the foot in rats, but osthol did not affect the PGE content in
the inflammatory tissues of the swollen part of the foot in rats.
Effects on the nervous system
The total coumarin of cnidium cnidium has an inhibitory effect on central nervous system. Osthol can significantly
enhance the hypnotic effect of pentobarbital sodium on subthreshold hypnotic dose in mice, and this hypnotic effect
is dose-related. Cnidium cnidium can promote the learning and memory of mice, and significantly improve the memory
acquisition, consolidation and direction discrimination of mice.
Anti - mutagenesis, anti - cancer effect
Cnidium, parsley b, bergamot lactone, isorhein, zanthoxylum acetaminophen and zanthoxylum toxin have high activity
in inhibiting the mutagenesis of aflatoxin B1. Water extract of cnidium could inhibit S130 sarcoma, prolong survival days
and inhibit tumor growth.
Skin Care Products and cosmetics
It has strong pharmacological activity and is an effective pharmaceutical ingredient that can be used in the pharmaceutical industry.
Water extract and total coumadin from fructus cnidium have obvious preventive effects on chloroform
induced ventricular fibrillation in mice and calcium chloride induced ventricular fibrillation in rats. Fructus
cnidium and zanthoxylum acetaminophen also have this pharmacological effect and can improve ventricular
electrofibrillation threshold in rabbits. The water extract, total coumarin, cnidium, and phenols of zanthoxylum
had significant inhibitory effects on the flow of sodium ions in the myocardial cell membrane.
Antihypertensive, inhibition of vascular dilatation
Osthol had a dose-dependent negative inotropic effect on the left atrium of isolated guinea pigs and a negative
frequency effect on the left atrium of isolated guinea pigs. In addition to the polarization induced by norepinephrine,
CaCl2 and high K+, the aorta contraction dose-response curve of rabbits was shifted to the right and the maximum
response was decreased, indicating the role of biosynthetic compound in relaxing vascular smooth muscle. Fructus
cnidium has a certain antihypertensive effect.
Effects on respiratory system
Cnidium monnieri total coumarin with relaxation by drugs (histamine and acetylcholine) caused by bronchial
spasms and diastole bronchus role directly, this function can be B - adrenaline receptor blockers block by propranolol,
mice after total coumarin cnidium monnieri, obviously increase the amount of phenol red drain in the body, shows
strong expectoranting action.
Anti-Inflammatory effects
Cnidium cnidium and phenolic zanthoxylum could inhibit the ear shell swelling of mice caused by xylene and the
increase of capillary permeability in abdominal cavity caused by acetic acid. Osthol and acetonol had significant
inhibitory effects on foot swelling in rats and rats with bilateral adrenal resection. Osthol could also reduce the PGE
content in the inflammatory tissues of the swollen part of the foot in rats, but osthol did not affect the PGE content in
the inflammatory tissues of the swollen part of the foot in rats.
Effects on the nervous system
The total coumarin of cnidium cnidium has an inhibitory effect on central nervous system. Osthol can significantly
enhance the hypnotic effect of pentobarbital sodium on subthreshold hypnotic dose in mice, and this hypnotic effect
is dose-related. Cnidium cnidium can promote the learning and memory of mice, and significantly improve the memory
acquisition, consolidation and direction discrimination of mice.
Anti - mutagenesis, anti - cancer effect
Cnidium, parsley b, bergamot lactone, isorhein, zanthoxylum acetaminophen and zanthoxylum toxin have high activity
in inhibiting the mutagenesis of aflatoxin B1. Water extract of cnidium could inhibit S130 sarcoma, prolong survival days
and inhibit tumor growth.
Skin Care Products and cosmetics
It can inhibit the formation of various inflammatory factors and has a good therapeutic effect on facial acne and acne.
For allergic skin diseases, such as eczema, urticaria has a good effect, can be used in anti - allergic cosmetics.
Dermatological drugs
Osthole has antispasmodic, antihypertensive, antiarrhythmic, immune function and broad-spectrum Antibacterial effects.It has strong pharmacological activity and is an effective pharmaceutical ingredient that can be used in the pharmaceutical industry.
Pesticides and pesticides
As a new type of biological pesticide, it can inhibit pests and plant pathogens. It is an effective botanical insecticide.
Q1: Can i get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments?
A: Payment by T/T, Western Union or Paypal
Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost
How to order
1. Make sure your quantity need and Leave us message, with your mailed details shown: Including
contact name, address information, contact phone, etc.
2. We send you a PI (Proforma Invoice) for price and payment detail.
3. Payment by Paypal or Western Union or T/T.
4. We arrange the delivery and update you the tracking number in time.
Product Categories : Herbal Extract Cnidium Fruit Extract
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